The viral load monitoring cascade in a resource-limited setting: A prospective multicentre cohort study after introduction of routine viral load monitoring in rural Lesotho

Viral load testing in resource-limited settings.

Monitoring HIV Viral Load in Resource Limited Settings: Still a Matter of Debate?

INTRODUCTION Consequences of lack of viral monitoring in predicting the effects of development of HIV drug resistance mutations during HAART in resource-limited settings (RLS) is still a matter of debate. DESIGN To assess, among HIV+ patients receiving their first-line HAART, prevalence of virological failure and genotypic resistance mutations pattern in a Médécins Sans Frontières/Ministry of...

Viral load monitoring in resource-limited settings: a medical and public health priority.

When antiretroviral therapy (ART) scale up began in Africa a decade ago, there was concern that lack of laboratory monitoring for patients receiving antiretroviral drugs would be an obstacle to providing treatment. To address this concern, the first set of World Health Organization (WHO) guidelines for ART in resource-limited settings rightly recommended that programmes should primarily use cli...

HIV-1 viral load monitoring: an opportunity to reinforce treatment adherence in a resource-limited setting in Thailand.

This paper describes a program to increase patients' treatment literacy regarding viral load (VL) monitoring through patient education materials and a counseling protocol, implemented by peer counselors, in order to reinforce adherence to first-line treatment. VL monitoring and second-line antiretroviral treatment were introduced into an established first-line treatment program in a rural distr...

Viral load monitoring of antiretroviral therapy, cohort viral load and HIV transmission in Southern Africa: a mathematical modelling analysis.

OBJECTIVES In low-income settings, treatment failure is often identified using CD4 cell count monitoring. Consequently, patients remain on a failing regimen, resulting in a higher risk of transmission. We investigated the benefit of routine viral load monitoring for reducing HIV transmission. DESIGN Mathematical model. METHODS We developed a stochastic mathematical model representing the co...